Prof. Nuno Osório

Universidade do Minho

Nuno S. Osório (37 years old) started his research work at Wageningen University, Holland, where he did an internship on the study of virulence factors of pathogenic microorganisms with Prof. Willem van Schaik. In 2009, he concluded his PhD at the University of Minho, Portugal, under the supervision of Prof. Fernando Rodrigues. Nuno's PhD work advanced the knowledge on the pathological mechanisms of Batten disease going from microbial to more complex model systems. His research was developed in part at the Rochester University Medical Center, USA and at the Center for Neuroscience and Cell Biology, University of Coimbra, Portugal. He went then to do a post-doctoral fellow under the supervision of Prof. Margarida Saraiva and obtained pioneering evidence for diversifying selection in Mtb. In 2015, he got an assistant investigator position at ICVS and created a research team named EvoBioMed (evobiomed.com). It focus on the evolution and genetic diversity of the obligate intracellular human pathogens Mtb and HIV-1. Its overarching aim is the use Bioinformatics-driven approaches to analyse ‘omics’ and clinical data to decipher molecular targets and instruct novel ways to fight Mtb and HIV-1. Presently, Nuno leads a multidisciplinary team of 8 researchers translating bioinformatics studies on human pathogen evolution towards medical discovery.