Prof. Dr. Aykut ÖZKUL

Ankara University


Adı : AYKUT
Soyadı : ÖZKUL
E-posta : ozkul@ankara.edu.tr
Tel : +312(0)317 0315 Ext 4364
Ünvan : PROF.DR.
Birim : VETERİNER FAKÜLTESİ
Bölüm : KLİNİK ÖNCESİ BİLİMLER BÖLÜMÜ

 

 

Kişisel Akademik Bilgiler
EĞİTİM

 

 

YIL EĞİTİM KURUMU DERECE ŞEHİR
 

1987-1992

Ankara Üniv. Veteriner Fakültesi Viroloji Anabilim Dalı  

Doktora

 

ANKARA

 

1982-1987

Ankara Üniv.

Veteriner Fakültesi

Lisans ve

Y. Lisans

 

ANKARA

 

 

İŞ TECRÜBESİ

 

 

YIL FAKÜLTE / KURUM ÜNVAN ŞEHİR
       
 

2003-

Viroloji Anabilim Dalı Veteriner Fak.

Ankara Üniversitesi

 

Profesör

 

ANKARA

 

1996-2003

Viroloji Anabilim Dalı Veteriner Fak.

Ankara Üniversitesi

 

Doçent

 

ANKARA

 

1995-1996

Mikrobiyoloji Bölümü Gülhane Askeri Tıp Akademisi Geçici Askeri Hizmet  

ANKARA

 

1992-1995

Viroloji Anabilim Dalı Veteriner Fak.

Ankara Üniversitesi

Doktora Sonrası Araştırıcı

Vet. Hek., Doktora, Yüksek Lisans

 

ANKARA

 

1987-1992

Viroloji Anabilim Dalı Veteriner Fak.

Ankara Üniversitesi

Doktora Öğrencisi

(Araş. Gör.)

Vet. Hek., Yüksek Lisans

 

ANKARA

 

 

YURTDIŞI ÇALIŞMALARI

 

YIL KURUM AKTİVİTE
 

2001

Hayvan Sağlığı Enstitüsü

Pirbright Lab, Morbillivirus lab.

Türkiye ile sınırlandırılmış hayvan morbilliviruslerin filogenetik analizi (PPRV, RPV ve CDV)
 

1999

Kansas Eyalet Üniversitesi

Veteriner Fak.

DMP

Doktora Sonrası araştırıcı. Tavşan modelinde BHV-5 nöroinvazifliği ve nörovirulensi üzerine gE’nin etkisinin araştırılması.
 

1994

 

Viroloji Enstitüsü, Hannover Veteriner Okulu, Almanya

Yeni izole edilen pestivirusların MoAb kullanılarak karakterizasyonu ve purfikasyonu,

RT-PCR ile gen duplikasyonu ve inzersiyonların araştırılması.

 

1991

 

Viroloji Enstitüsü, Hannover Veteriner Okulu, Almanya

Direk IP testi uygulaması,

BVDV’ye karşı Ip ve IF konjugatların hazırlanması

BVDV’ye karşı üretilen MoAb’ların pürifikasyonu ve karakterizasyou

 

 

ÜYELİKLER

 

YIL

(beri)

BİLİMSEL/PROFESYONEL

KURULUŞ

2010 American Society for Microbiology
1991 European Society for Veterinary Virology
1990 TÜRK BUIATRI Derneği
1988 Türk Veteriner Mikrobiyoloji Derneği

 

 

 

 

 

 

 

 

 

İDARİ GÖREVLER

 

 

GÖREV KURUM DÖNEM (YIL)
Müdür Ankara Üniversitesi, Biyoteknoloji Enstitüsü 2012 –
Yönetim Kurulu Üyesi Ankara Üniversitesi, Veteriner Fakültesi 2008-2012
Müdür Yardımcısı Ankara Üniversitesi, Biyoteknoloji Enstitüsü 2008

(6 ay)

Yönetim Kurulu Üyesi Ankara Üniversitesi, Biyoteknoloji Enstitüsü 2007-2008

 

 

ÖDÜLLER

 

 

Türk Veteriner Hekimler Birliği Bilim Ödülü (2007)

Novartis Bilim Ödülü (2011)

 

 

MAKALELER

ERGUNAY K, LITZBA N, BRINKMANN A, GUNAY F, SARIKAYA Y, KAR S, ORSTEN S, OTER K, DOMINGO C, KASAP OE. OZKUL A, MITCHELL L, NITSCHE A, ALTEN B, LINTON YM. Co-circulation of West Nile virus and distinct insect-specific flaviviruses in Turkey, Parasites & Vectors,10,1,149,2017.

 

DEMIR Z C, BASTUG A BODUR H, ERGUNAY K, OZKUL, A. MicroRNA expression profiles in patients with acute Crimean Congo hemorrhagic fever reveal possible adjustments to cellular pathways, Journal of medical virology,89,3,417-422,2017.

 

DINCER E, KARAPINAR Z, OKTEM M, OZBABA M, OZKUL A, ERGUNAY K. Canine infections and partial S segment sequence analysis of Toscana virus in Turkey. Vector-Borne and Zoonotic Diseases,16,9,611-618,2016.

 

WEIDMANN M, AVSIC-ZUPANC T, BINO S, BOULOY M, BURT F, CHINIKAR S, CHRISTOVA I, DEDUSHAJ I, EL-SANOUSI A, ELALDI N, HEWSON R, HUFERT FT, HUMOLLI I, JANSEN VAN VUREN P, KOCAK TUFAN Z, KORUKLUOGLU G, LYSSEN P, MIRAZIMI A, NEYTS J, NIEDRIG M, OZKUL A, PAPA A, PAWESKA J, SALL AA, SCHMALJOHN CS, SWANEPOEL R, UYAR Y, WEBER F, ZELLER H. Biosafety standards for working with Crimean-Congo hemorrhagic fever virus, Journal of General Virology,97,11,2799-2808,2016

 

EREN D, ONGUT G, COLAK D, OZKUL, A, MUTLU D, ZEYTINOGLU A, MIDILLI K, GOKAHMETOGLU S, GUNSEREN F, OGUNC D. Determination of cytomegalovirus glycoprotein B genotypes in different geographical regions and different patient groups in Turkey. Mikrobiyoloji bulteni, 2016, 50,1,53-62.

 

TEZCAN S, DINCER E, ULGER M, OZGUR D, ERDOGAN S, OZKUL A, EMEKDAS G, ERGÜNAY K. [Serological investigation of phlebovirus exposure in blood donors from the Mediterranean Province of Mersin, Turkey]. Mikrobiyol Bul. 2015 Jul;49(3):403-13.

 

ERGUNAY K, KAPLAN B, OKAR S, AKKUTAY-YOLDAR Z, KURNE A, ARSAVA EM, OZKUL A. Urinary detection of toscana virus nucleic acids in neuroinvasive infections. J Clin Virol. 2015;70:89-92. doi: 10.1016/j.jcv.2015.07.297.

 

TUGCU-DEMIROZ F, ACARTURK F, OZKUL A. Preparation and characterization of bioadhesive controlled-release gels of cidofovir for vaginal delivery. J Biomater Sci Polym Ed. 2015;26(17):1237-55. doi: 10.1080/09205063.2015.1082808.

 

LEBLEBICIOGLU H, SUNBUL M, MEMISH ZA, AL-TAWFIQ JA, BODUR H, OZKUL A, GUCUKOGLU A, CHINIKAR S, HASAN Z. Consensus report: Preventive measures for Crimean-Congo Hemorrhagic Fever during Eid-al-Adha festival. Int J Infect Dis. 2015 38:9-15. doi: 10.1016/j.ijid.2015.06.029.

 

ERGUNAY K, KARAGUL A, ABUDALAL A, HACIOGLU S, US D, ERDEM Y, OZKUL A. Prospective investigation of the impact of West Nile Virus infections in renal diseases. J Med Virol. 2015 Oct;87(10):1625-32. doi:10.1002/jmv.24226.

 

DINCER E, GARGARI S, OZKUL A, ERGUNAY K. Potential animal reservoirs of Toscana virus and coinfections with Leishmania infantum in Turkey. Am J Trop Med Hyg. 2015 Apr;92(4):690-7. doi: 10.4269/ajtmh.14-0322.

 

ERGUNAY K, BAKONYİ T, NOWOTNY N, OZKUL A. Close Relationship between West Nile Virus from Turkey and Lineage 1 Strain from Central African Republic. Emerg Infect Dis. 2015 Feb;21(2):352-355. doi: 10.3201/eid2102.141135.

 

DINCER, E., OZKUL, A. Development of real-time reverse transcriptase-polymerase chain reaction (rt RT-PCR) targeting four genes of peste des petits ruminants virus. Ankara Üniversitesi Veteriner Fakültesi Dergisi (2015), 62 (4): 283-287

 

JÄÄSKELÄİNEN AJ, KALLİO-KOKKO H, OZKUL A, BODUR H, KORUKRUOGLU G, MOUSAVİ M, PRANAV P, VAHERİ A, MİRAZİMİ A, VAPALAHTİ O. Development and Evaluation of a Real-Time RT-qPCR for Detection of Crimean-Congo Hemorrhagic Fever Virus Representing Different Genotypes. Vector Borne Zoonotic Dis. 2014
Dec;14(12):870-2. doi: 10.1089/vbz.2014.1577.

 

ERGUNAY K, KASAP O, ORSTEN S, OTER K, GUNAY F, YOLDAR A, DİNCER E, ALTEN B, OZKUL A. Phlebovirus and Leishmania detection in sandflies from eastern Thrace and northern Cyprus. Parasit Vectors. 2014 Dec 12;7(1):575.

 

ERTILAV M, OZKUL A, ZEYTINOĞLU A, SEN S, SIPAHI S, TÖZ H, KITIŞ O, ERASLAN C. Meningoencephalitis caused by West Nile virus in a renal transplant recipient. Mikrobiyol Bul. 2014 Oct;48(4):674-82.

 

TEZCAN S, KIZILDAMAR S, ULGER M, ASLAN G, TİFTİK N, OZKUL A, EMEKDAŞ G, NİEDRİG M, ERGÜNAY K. [Flavivirus seroepidemiology in blood donors in Mersin
province, Turkey]. Mikrobiyol Bul. 2014 Oct;48(4):606-17.

 

OCAL M, ORSTEN S, INKAYA AC, YETİM E, ACAR NP, ALP S, KASAP OE, GUNAY F, ARSAVA EM, ALTEN B, OZKUL A, US D, NİEDRİG M, ERGUNAY K. Ongoing activity of Toscana virus genotype A and West Nile virus lineage 1 strains in Turkey: a
clinical and field survey. Zoonoses Public Health. 2014 Nov;61(7):480-91. doi:
10.1111/zph.12096.

 

KANTARCİ FA, FARAJİ AR, OZKUL A, AKATA F. Evaluation of the effects of
acyclovir and/or human amniotic membrane on herpes virus culture and quantitative
virus inactivity by real-time polymerase chain reaction. Int J Ophthalmol. 2014
Aug 18;7(4):626-31. doi: 10.3980/j.issn.2222-3959.2014.04.07.

 

ERGUNAY K, GUNAY F, ERİSOZ KASAP O, OTER K, GARGARİ S, KARAOGLU T, TEZCAN S, CABALAR M, YİLDİRİM Y, EMEKDAS G, ALTEN B, OZKUL A. Serological, molecular and entomological surveillance demonstrates widespread circulation of West Nile virus in Turkey. PLoS Negl Trop Dis. 2014 Jul 24;8(7):e3028. doi: 10.1371/journal.pntd.0003028.

 

ERGUNAY K, KOCAK TUFAN Z, BULUT C, KİNİKLİ S, DEMİROZ AP, OZKUL A. Antibody responses and viral load in patients with crimean-congo hemorrhagic fever: a
comprehensive analysis during the early stages of the infection. Diagn Microbiol
Infect Dis. 2014 May;79(1):31-6. doi: 10.1016/j.diagmicrobio.2013.12.015.

 

OKTEM IM, UYAR Y, DİNCER E, GOZALAN A, SCHLEGEL M, BABUR C, CELEBİ B, SOZEN M, KARATAS A, OZKAZANC NK, MATUR F, KORUKLUOGLU G, ULRİCH RG, ERTEK M, OZKUL A. Dobrava-Belgrade virus in Apodemus flavicollis and A. uralensis mice, Turkey. Emerg Infect Dis. 2014 Jan;20(1):121-5. doi: 10.3201/eid2001.121024.

 

ERGUNAY K, GUNAY F, OTER K, KASAP OE, ORSTEN S, AKKUTAY AZ, ERDEM H, OZKUL A, ALTEN B. Arboviral surveillance of field-collected mosquitoes reveals circulation of West Nile virus lineage 1 strains in Eastern Thrace, Turkey. Vector Borne
Zoonotic Dis. 2013 Oct;13(10):744-52. doi: 10.1089/vbz.2012.1288.

 

ERDEM H, ERGUNAY K, YİLMAZ A, NAZ H, AKATA F, INAN AS, ULCAY A, GUNAY F, OZKUL A, ALTEN B, TURHAN V, ONCUL O, GORENEK L. Emergence and co-infections of West Nile virus and Toscana virus in Eastern Thrace, Turkey. Clin Microbiol Infect. 2014 Apr;20(4):319-25. doi: 10.1111/1469-0691.12310.

 

SAĞLIK I, MUTLU D, ONGÜT G, VELİPAŞAOĞLU GÜNEY S, OZKUL A, OĞÜNÇ D, COLAK D. [Investigation of adenoviruses in children with lower respiratory tract
infections]. Mikrobiyol Bul. 2013 Apr;47(2):282-94. Turkish.

 

OZKUL A, ERGUNAY K, KOYSUREN A, ALKAN F, ARSAVA EM, TEZCAN S, EMEKDAS G, HACİOGLU S, TURAN M, US D. Concurrent occurrence of human and equine West Nile virus infections in Central Anatolia, Turkey: the first evidence for circulation of lineage 1 viruses. Int J Infect Dis. 2013 Jul;17(7):e546-51. doi:
10.1016/j.ijid.2013.02.005.

 

MERTENS M, SCHMİDT K, OZKUL A, GROSCHUP MH. The impact of Crimean-Congo hemorrhagic fever virus on public health. Antiviral Res. 2013 May;98(2):248-60.
doi: 10.1016/j.antiviral.2013.02.007

 

OCAL M, ONDER H, ARSAVA EM, ALP S, OZKUL A, ERGÜNAY K. [A case of central nervous system infection due to west nile virus lineage-1 in ankara province,
Turkey]. Mikrobiyol Bul. 2013 Jan;47(1):164-72. Turkish.

 

KARAKAS A, OGUZOGLU TC, COSKUN O, ARTUK C, MERT G, GUL HC, SENER K, OZKUL A. First molecular characterization of a Turkish orf virus strain from a human based on a partial B2L sequence. Arch Virol. 2013 May;158(5):1105-8. doi:
10.1007/s00705-012-1575-5.

 

YESİLBAG K, AYDİN L, DİNCER E, ALPAY G, GİRİSGİN AO, TUNCER P, OZKUL A. Tick survey and detection of Crimean-Congo hemorrhagic fever virus in tick species
from a non-endemic area, South Marmara region, Turkey. Exp Appl Acarol. 2013
Jun;60(2):253-61. doi: 10.1007/s10493-012-9642-x.

 

YEŞİLKAYA A, KURT AZAP O, AARSLAN H, YAĞCI ÇAĞLAYIK D, UYAR Y, KORUKLUOĞLU G, OZKUL A. [A fatal case of West Nile virus encephalitis]. Mikrobiyol Bul. 2012 Jul;46(3):488-92. Turkish.

 

OZKUL, A.,  ERGUNAY, K.,  KOYSUREN, A., ALKAN, F., ARSAVA,  E. M., TEZCAN, S., EMEKDAS, G., HACIOGLU, S., TURAN, M., US, D. Concurrent occurrence of human and equine west nile virus infections in central Anatolia, turkey: the first evidence for circulation of lineage 1 viruses. Int J Infect Dis,

 

ERGUNAY K, SAYINER AA, LITZBA N, LEDERER S, CHARREL R, KREHER P, US D, NIEDRIG M, OZKUL A, HASCELIK G. Multicentre evaluation of Central Nervous system infections due to Flavi and Phleboviruses in Turkey. J Infect. 2012 Jun 13.

 

KALAYCIOGLU H, KORUKLUOGLU G, OZKUL A, ONCUL O, TOSUN S, KARABAY O, GOZALAN A, UYAR Y, CAGLAYIK D, ATASOYLU G, ALTAS A, YOLBAKAN S, OZDEN T, BAYRAKDAR F, SEZAK N, PELITLI TS, KURTCEBE Z, AYDIN E, ERTEK M. Emergence of West Nile virus infections in humans in Turkey, 2010 to 2011. Euro Surveill. 2012 May 24;17(21). pii: 20182.

 

ERGUNAY K, ERISOZ KASAP O, KOCAK TUFAN Z, TURAN MH, OZKUL A, ALTEN B. Molecular evidence indicates that Phlebotomus major sensu lato (Diptere: Psychodidae) is the vector species of the recently-identified Sandfly Fever Turkey Virus. Vector Borne Zoonotic Dis. 2012 May 31.

 

MAHZOUNIEH, M., DINCER, E., FARAJI, A., AKIN, H., AKKUAY, A.Z.,  OZKUL, A.,Relationship between Crimean-Congo Hemorrhagic Fever Virus strains Circulating in Iran and Turkey: Possibilities for transborder transmission. Vector Borne Zoonotic Dis. 2012

 

KALAYCIOGLU, A.T., DURMAZ, R., UYAR, Y., UNALDI, O., AKSEKILI, E., OZKUL, A., KORUKLUOGLU, G., ERTEK, M., Lack of genetic diversity in Crimean-Congo hemorrhagic fever viruses in Turkey: Assessment of present and future patterns of disease. J Med Virol, 2012 Mar;84(3):471-8. doi: 10.1002/jmv.22224.

 

KUBAR A, HACIOMEROGLU M, OZKUL A, BAGRIACIK U, AKINCI E, SENER K, BODUR H. Prompt Administration of Crimean-Congo Hemorrhagic Fever (CCHF) Virus Hyperimmunoglobulin in Patients Diagnosed with CCHF and Viral Load Monitorization by Reverse Transcriptase-PCR. Jpn J Infect Dis. 2011 Sep;64(5):439-43.

 

ERGUNAY, K., AYDOGAN, S., ILHAMİ OZCEBE, O., CİLEK, E.E., HACİOGLU, S., KARAKAYA, J., OZKUL, A., US, D. Toscana Virus (TOSV) exposure is confirmed in blood donors from Central, North and South/Southeast Anatolia, Turkey.Zoonoses Public Health. 2011 Sep 14. doi: 10.1111/j.1863-2378.2011.01436.x.

 

HEKIMOGLU, O., OZER, N., ERGUNAY, K., OZKU,L A. Species distribution and detection of Crimean Congo Hemorrhagic Fever Virus (CCHFV) in field-collected ticks in Ankara Province, Central Anatolia, Turkey. Exp Appl Acarol. 2011, DOI 10.1007/s10493-011-9492-y

 

CEYLAN, C., SEVERCAN, F., OZKUL, A., SEVERCAN, M., BOZOGLU, F., TAHERI, N. Biophysical and microbiological study of high hydrostatic pressure inactivation of Bovine Viral Diarrheavirus type 1 on serum. Vet Microbiol. 2011, doi:10.1016/j.vetmic.2011.07.026

 

ERGUNAY, K.,OZKUL, A.Confirmation of West Nile virus seroreactivity in central nervous system infections of unknown etiology from Ankara Province, Central Anatolia, Turkey. Mikrobiyol Bul. 2011 Apr;45(2):381-3

 

ERES, G., ALTIOK, E., OZKUL, A., ACIKEL, C.H. Subgingival Epstein Barr and Cytomegalovirus Occurrence in Pregnancy Gingivitis. J Periodontol. (2011) doi:10.1902/jop.2011100587

 

TEZER, H., TAVIL, B., SUCAKLI, I.A., KORUKLUOGLU, G., UYAR ,Y., DINCER E., TUNC, B., OZKUL, A. Concurrent Crimean-Congo hemorrhagic fever and visceral leishmaniasis in a Turkish girl. Vector Borne Zoonotic Dis. 2011 Jun;11(6):743-5

 

ERGUNAY, K., WHITEHOUSE, C., OZKUL, A. Current status of human arboviral diseases in Turkey. Vector-Borne and Zoonotic Diseases. (2010) DOI: 10.1089/vbz.2010.0162.

 

GUNBEYAZ, M., FARAJI, A., OZKUL, A., PURALI, N., SENEL, S., Chitosan Based Delivery Systems For Mucosal Immunization Against Bovine Herpesvirus 1 (BHV-1), European Journal of Pharmaceutical Sciences(2010), 41: 531-45.

 

ERGUNAY, K., AYDOGAN, S., MENEMENLIOGLU, D., SENER, B., LEDERER, S., STEINHAGEN, K., HASCELİK, G., PINAR, A., OZKUL, A., US, D. Investigation of West Nile virus in central nervous system infections of unknown etiology in Ankara, Turkey. Mikrobiyol Bul. (2010), 44(2): 255-62.

 

UTKU, S., GUMUS, F., TEZCAN, S., SERIN, M.S., OZKUL, A. Synthesis, characterization, cytotoxicity and DNA binding of some new platinium(II) and platinium(IV) complexes with benzimidasole ligands. J Enzyme Inhib Med Chem. 2010 Aug;25(4):502-8.

 

OZKAYA, E., DINCER, E., CARHAN, A., UYAR, Y., ERTEK, M., WHITEHOUSE, C., OZKUL, A. Molecular epidemiology of Crimean-Congo hemorrhagic fever virus in Turkey: Occurrence of local topotype. Virus Res (2010);149(1):64-70.

 

ALKAN, F., OZKUL, A., OGUZOGLU, T.C., TIMURKAN, M.O., CALISKAN, E., MARTELLA, V., BURGU, I. Distribution of G (VP7) and P (VP4) genotypes of group A bovine rotaviruses from Turkish calves with diarrhea, 1997-2008., Vet Microbiol., (2010) 141:231-237.

 

ERGUNAY, K.,  SAYGAN, M. B., AYDOGAN, S., MENEMENLIOGLU, D., TURAN, H.M. OZKUL, A.,US, D. West Nile virus (WNV) seroprevalence in blood donors from Central Anatolia, Turkey. Vector-Borne and Zoonotic Diseases. (2010), 10(8): 771-775.

 

SENER, K., YAPAR, M., OZKUL, A., KORU, O., KUBAR, A. Detection of West Nile Virus RNA by One-Step Real Time RT-PCR. Am J Trop Med Hyg, 2009, 81:5 (Supl), 234.

 

OZKUL, A., ERTURK, A., CALISKAN, E., SARAC, F., CEYLAN, C., MERTENS, P., KABAKLI, O., DINCER, E., CIZMECI, S.G. Segment 10 based molecular epidemiology of bluetongue virus (BTV) isolates from Turkey: 1999-2001. Virus Res. (2009), 142 (1-2), 134-9

 

GUMUS, F., EREN, G., ACIK, L., CELEBI, A., OZTURK, F., YILMAZ, S., SAGKAN, R.I,, GUR, S,, OZKUL, A., ELMALI, A., ELERMAN, Y.  Synthesis, Cytotoxicity, and DNA Interactions of New cisplatin Analogues Containing Substituted Benzimidazole Ligands. J Med Chem. (2009) 52: 1354-1357.

 

OGUZOGLU, T.C., TAN, M.T., TOPLU, N., DEMIR, A.B., BILGE-DAGALP, S., KARAOGLU, T., OZKUL, A., ALKAN, F., BURGU, I., HAAS, L., GREISER,-WILKE, I. Border Disease virus (BDV) infections of small ruminants in Turkey: A new BDV subgroup? Vet Microbiol (2009), 135(3-4):374-379.

 

YEŞİLBAĞ, K., FÖRSTER, C., BANK-WOLF, B., YILMAZ, Z., ALKAN, F., OZKUL, A.,  BURGU, İ., ROSALES, S.C., THIEL, H.J., KÖNIG, M. Genetic heterogeneity of Bovine Viral Diarrhea Virus (BVDV) isolates from Turkey: Identification of a new subgroup in BVDV-1. Vet Microbiol (2008), 130: 258-267.

 

ÖZKUL, A., ATLAŞ, B., KARAOĞLU, T., ALKAN, F., DİNÇER, E., ONCEL, T., BURGU, İ. Maturation Of Immunoglobulin G Avidity After Inactive gE Deleted Bovine Herpesvirus Type 1 (BHV-1) Marker Vaccination. Viral  Immunol, (2008) 21 (1): 3-11.

 

KUL, O., KABAKCI, N., ÖZKUL, A. KALENDER, K., ATMACA, H.T. Concurrent peste des petits ruminants virus and pestivirus infection in stillborn twin lambs Vet. Pathol. (2008) 45 (2): 191-196.

 

PURSE, B.V., MELLOR , P.S., BAYLIS , M.,, MCCORMICK , B.J.J., ROGERS , D.J., BOORMAN, J.P.T.,  BORRAS, D., BURGU, I., CAPELA, R., CARACAPPA, S., COLLANTES, S., DE LIBERATO, C., DELGADO, J.A., DENİSON, E., GEORGIEV, G., HARAK, M., ROCQUE, S., LHOR, Y., LUCIENTES, J., MANGANA, O., MIRANDA, M.A., NEDELCHEV, N., NOMIKOU, K.,  OZKUL, A., PATAKAKIS, M., PENA, I., SCARAMOZZINO, P., TORINA A. Incriminating bluetongue virus vectors with climate envelope models. J Appl Ecol  (2007) 44: 1231-1242.

 

ERGUNAY, K.,  OZER, N., US, D., OZKUL, A., SİMSEK, F., KAYNAS, S., USTACELEBİ, S. Seroprevalence of West Nile virus and tick-borne encephalitis virus in southeastern Turkey: first evidence for tick-borne encephalitis virus infections. Vector-Borne and Zoonotic Diseases. (2007) 7(2): 157-162. doi:10.1089/vbz.2006.0574.

 

KUL, O., KABAKÇI, N., ATMACA, H.T., OZKUL, A. Natural Peste des Petits Ruminantns Virus Infection: Novel pathologic findings resembling other Morbillivirus Infections. Vet Path (2007) 44: 479-486.

 

YESILBAG, K., YILMAZ, Z., OZKUL, A., PRATELLI, A   Aetiological role of viruses in puppies with diarrhoea. Vet Rec, (2007).161(5):169-70.

 

GUNGOR, A.B., OZKUL, A. Dynamics of natural Bovine Herpesvirus-1 (BoHV-1) infection in a dairy herd. Trop Anim Health Prod, (2007).39:13-20.

 

OGUZOGLU,T.C., ALKAN, F., OZKUL,A., ATALAY VURAL, S., GUNGOR,A.B. and BURGU,I  A Sheep Poxvirus Outbreak in Central Turkey in 2003: Isolation and Identification of Capripoxvirus ovis. Vet Res Com. (2006), 30, 965-971.

 

OZKUL, A., YILDIRIM, Y., PINAR, D., AKCALI, A., YILMAZ, V., COLAK, D. Serological Evidence of West Nile Virus (WNV) in Mammalian Species in Turkey. Epidemiol Infect, (2006), 134,826-829

 

CAM, Y., GENCAY, A., BEYAZ, L., ATALAY, O., ATASEVEN, A., OZKUL, A., KIBAR M. Peste des Petits ruminants (PPR) in a sheep and goat flock in Kayseri province in Turkey. Vet Rec, (2005). 157(17):523-4.

 

BASKIN, Y., YAZICI, Z., BASKIN, H., GEÇER, O., OZKUL, A., OLGUN, N., BAHAR, H.I. Selective apoptotic behaviour of bovine herpesvirus – 1 in an epithelial like microenvironment. Act. Vet. Hung, (2005).53(4), 479-491

 

BASKIN, H. , YAZICI, Z,  BASKIN, Y., OLGUN, N.,. OZKUL , A.,  BAHAR, I. H. Effects of non toxic doses of acyclovir on nitric oxide and cellular death responses in Herpesvirus Type 1 and 2 infected Hep-2 cells. The New Microbiologica, (2005) 28: 205-213.

 

GÜLYAZ, V. ÖZKUL, A. Pathogenicity of a local PPR virus isolate in sheep in Turkey. Trop Anim Health Prod,  (2005) 37: 541-547.

 

YESILBAG, K., YILMAZ, Z., GOLU, E., OZKUL, A. Peste des Petits Ruminants (PPR) outbreak in Bursa province, western Turkey, Vet Rec (2005). 157: 260-261.

 

UZEL, M., SASMAZ, S., BAKARIS, S., CETINUS, E., BILGIC, E., KARAOGUZ, A., OZKUL, A.,ARICAN. O. (2005). A viral infection of the hand commonly seen after the feast of sacrifice: human orf (orf of the hand). Epidemiol Infect. 133: 653-657.

 

BAILEY, D., BANYARD, A., DASH, P., OZKUL, A., BARRETT, T. (2005) Full genome sequence of Peste des Petits Ruminants virus, a member of  the Morbillivirus genus. Virus Research 110, 119–124.

 

KOSE, G.T., KORKUSUZ, F., OZKUL, A., SOYSAL, Y., OZDEMIR, T., YILDIZ, C., HASIRCI, V. (2005) Tissue engineered cartilage on collagen and PHBV matrices.
Biomaterials. 26 (25):5187-97.

 

GOKCE, M., UTKU, S., GÜR, S., OZKUL, A., GUMUS, F. (2005) Synthesis, in vitro cytotoxic and antiviral activity of cis-[Pt(R(-) and S(+)-2-α-hydroxybenzylbenzimidazole)2Cl2] complexes. Eur J Med Chemistry, 40: 135–141.

 

GENCAY, A., ONCEL, T., KARAOGLU, T., SANCAK, A.A., DEMIR, B., OZKUL, A. (2004). Antibody prevalence to Canine Distemper Virus (CDV) in stray dogs in Turkey. Rev Med Vet, 155, 432–434.

 

YAZICI, Z., BASKIN, Y., BASKIN, H., GECER, Ö., BAHAR, İ.H.,ÖZKUL, A. (2004) Study of programmed cell death in Bovine Herpesvirus 1 infected MDBK cells and the possible role of nitric oxide in this process. Acta Vet Hung, 52: 287–297.

 

UZEL, M., SASMAZ, S., OZKUL, A., CETİNUS, E., BİLGİC, E., KARAOGUZ, A. (2004). Swan-neck deformity and paresthesia following giant Orf. J Dermatology, 31: 116–118.

 

ÖZKUL, A., SANCAK, A.A., GUNGOR, E., BURGU, I. (2004). Determination and phylogenetic analysis of Canine Distemper Virus (CDV) in dogs with the nervous symptoms in Turkey. Acta Vet Hung, 52: 125–132.

 

KOSE, G.T., KORKUSUZ, F., KORKUSUZ, P., PURALI, N., OZKUL, A., HASIRCI, V. (2003) Bone generation on PHBV matrices: an in vitro study. Biomaterials, 24: 4999–5007.

 

GUMUS, F., PAMUK, I., OZDEN, T., YILDIZ, S., DIRIL, N., OKSUZOGLU, E., GUR, S., OZKUL, A. (2003) Synthesis, characterization and in vitro cytotoxic, mutagenic and antimicrobial activity of platinum(II) complexes with substituted benzimidazole ligands. J Inorg Biochem.. 94(3): 255–262.

 

GUMUS, F., ALGUL, O., EREN, G., EROGLU, H., DIRIL, N., GUR, S., OZKUL, A. (2003) Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands. Eur J Med Chem. 38(5):473–480.

 

BURGU, İ., ALKAN, F., ÖZKUL, A., YEŞİLBAĞ, K., KARAOĞLU, T., GÜNGÖR, B. (2003). Türkiye’de süt sığırcılığı işletmelerinde BVDV enfeksiyonunun epidemiyolojisi ve kontrolü. Ankara Üniv Vet Fark Derg, 50: 127–133.

 

KARAOĞLU, T., BURGU, İ., ÖZKUL, A.  (2003). Biotypic characterization of Bovine Virus Diarrhoea Virus (BVDV) using reverse transcription-polymerase chain reaction (RT-PCR) in clinical samples. Acta Vet Hung., 51: 425–431.

 

ÖZKUL, A., KELEŞ, İ., KARAOĞLU, T., ÇABALAR, M., BURGU, İ. (2002).  Detection and RFLP analysis of Canine Parvovirus (CPV) DNA by Polymerase Chain Reaction (PCR) in a Dog. Turk J Vet Anim Sci, 6: 1201–1203.

 

ÖZKUL, A.,YEŞİLBAĞ, K., BURGU, İ. (2002). Efficiency of four diagnostic techniques for detecting bovine virus diarrhoea virus (BVDV) in buffy coat samples after long term storage.  Turk J Vet Anim Sci, 26: 1043–1048.

 

ÖZKUL, A., AKÇA, Y., ALKAN, F., BARRETT, T., KARAOĞLU, T., DAĞALP, S.B., ANDERSON, J., YEŞILBAĞ, K., ÇOKÇALIŞKAN, C.,GENÇAY, A., BURGU, İ. (2002) Prevalance, distribution and host range of peste des petits ruminants virus in turkey. Emerg Inf Dis, 8(7): 708-712.

 

ÖZKUL, A.,YEŞİLBAĞ, K., KARAOĞLU, T., BURGU, İ. (2002). Electrophoretypes of Bovine rotaviruses detected in Turkey. Turk J Vet Anim Sci, 26: 359-362.

 

YEŞİLBAĞ, K., ÖZKUL, A., BURGU, İ. (2001). Farklı laboratuvarlarda aynı adla kullanılan BVDV suşları arasında antijrnik farklılıklar. AÜ Vet Fak Derg, 48(1):7-11.

 

BURGU, İ., AKÇA, Y., ALKAN, F., ÖZKUL, A., KARAOĞLU, T., BİLGE-DAĞALP, S., OĞUZOĞLU, Ç., YEŞİLBAĞ, K. (2001) Koyunlarda doğum öncesi ve sonrası dönemlerde BVD virus enfeksiyonunun serolojik, virolojik ve patogenez yönünden araştırılması. Turk J Vet Anim Sci, 25:551-557.

 

ÖZSAN, M., GÜNGÖR, Ç., KAHRAMAN, M., ÖZKUL, A., CİNEL, L., TEZCANER, T., YORGANCIOĞLU, C., SÜZER, K. (2000) Chlamydia and atherosclerotic coronary artery disease in Turkey. Acta Cardiol, 55: 295-300.

 

ALKAN, F., ÖZKUL, A., BİLGE-DAĞALP, S., YEŞİLBAĞ, K., OĞUZOĞLU, T.Ç. AKÇA, Y. and BURGU, İ. (2000) Virological and serological studies on the role of PI-3 virus, BRSV, BVDV and BHV-1 on respiratory infections of cattle. I. The detection of aetiological agents by direct immunoflourescence technique. Dtsch. Tierarztl. Wschr., 107: 193-195.

 

OZSAN, M., TEKELI, A., OZDEN, A., AKYON, Y., OZKUL, A., GERÇEKER, D., and CETINKAYA, H. (2000) Vacuolating cytotoxic activity of 40 Helicobacter pylori strains isolated from Turkish patients. APMIS, 108: 293-295.

 

CHOWDHURY, S.I., LEE, B. J., ÖZKUL, A. and WEISS, M. L. (2000) : Bovine Herpesvirus Type-5 glycoprotein E is important for neuroinvasiveness and neurovirulence in the olfactory pathway of the rabbit. J Virol, 74(5):2094-106.

 

BURGU, İ., AKÇA, Y., ALKAN, F., ÖZKUL, A., KARAOĞLU, T., YEŞİLBAĞ, K., OĞUZOĞLU, T.Ç., BİLGE-DAĞALP, S., ve TAN, M.T. (1999) : Klinik olarak sağlıklı veya diyare semptomlu koyunlarda rotavirus enfeksiyonunun ELISA ve PAGE teknikleri ile araştırılması. Ankara Üniv Vet Fark Derg, 46: 143-147.

 

ÖZSAN, M., ÖZKUL, A. ve CENGİZ, A.T. (1999) : Erişkinlerde Respiratory Syncytial Virus (RSV) nötralizan antikor prevalansının araştırılması. O.M.Ü. Tıp Dergisi, 16(1):43-46.

 

ÖZSAN, M., ÖZKUL, A., CENGİZ, A.T., KARAASLAN, A. ve AYKUT, E. (1999) : Erişkin yaş grubunda kabakulak antikorlarının hemaglutinasyon inhibisyon yöntemi ile araştırılması. Karadeniz Tıp Dergisi, 12(1): 42-44.

 

ERGÜN, G., DOĞAN. A., ÖZKUL, A. and DEMİREL, E. (1999) : Glass ionomer cement nad composite cements: Cytotoxicity Effect. Balkan J of Stomatology, 3(2):103-105.

 

ÖZSAN, M., ERBAY, B., ÖZKUL, A., ERTÜRK, Ş., KARAASLAN, A. ve ATEŞ, K. (1999) : Böbrek transplantasyonu yapılan hastalarda sitomegalovirus enfeksiyonunun serolojik ve klinik olarak takibi ve transplantasyon sonrası semptomatik enfeksiyon prevalansı. Mikrobiyol Bült., 33:127-134.

 

GÜNSEREN, F., ÇOLAK, D., ÖZKUL, A., MUTLU, G., SABA, R., BURGU, İ., MAMIKOĞLU, L., KARADOĞAN, İ. and ÜNDAR, L. (1998) : Detection of cytomegalovirus antigenemia in a patient with acute myeloblastik leukemia. Turkish J of Infection, 12(2):245-251.

 

ÖZSAN, M., AYKUT, E., CENGİZ, A.T., ÖZKUL, A. and KARAASLAN, A. (1998) : 0-5 yaş arasındaki çocuklarda kabakulak virus antikor pozitifliğinin araştırılması. Mikrobiyol Bült., 32:137-142.

 

ÖZSAN, M., ÖZKUL, A., KARAASLAN, A. ve CENGİZ, A.T. (1998) : 0-5 yaş grubu çocuklarda respiratory syncytial virus antikorlarının modifiye nötralizasyon yöntemi ile araştırılması. AÜ Tıp Fak Mecmuası, 51(4):187-189.

 

ÖZKUL, A. ve ÖZSAN, M. (1998) : Hücre kültürlerinde Respiratory Syncytial virus infeksiyonunun direkt immunoperoksidaz tekniği ile hızlı tanısı. Flora, 3(4):258-262.

 

ALKAN, F., ÖZKUL, A., KARAOĞLU, T.M., BİLGE, S., AKÇA,Y., BURGU, İ., YEŞİLBAĞ, K. ve OĞUZOĞLU, T.Ç. (1997) : Sığırlarda viral nedenli solunum sistemi enfeksiyonlarının seroepidemiyolojisi. AÜ Vet Fak Derg., 44(1):73-80.

 

ÖZSAN, M., ÖZKUL, A., CİCİOĞLU, B. and AYSEV, D. (1997): An investigation on the prevalence of rotavirus infection in children with diarrhoea using polyacrylamide gel electrophoresis (PAGE). Turk J Med Sci, 27:251-253.

 

AKÇA, Y., ALKAN, F., BİLGE, S., KARAOĞLU, T.M., ÖZKUL, A., BURGU, İ.,  KAADEN, O.R. (1996): Süt sığırlarının süt ve kan serumlarında Enzootik Sığır Löykozuna (EBL) karşı antikor varlığının ELISA ve AGID testi ile araştırılması. AÜ Vet Fak Derg., 43(1): 53-59.

 

ÖZKUL, A., ÇABALAR, M., BİLGE, S., AKÇA, Y. ve BURGU, İ. (1995) : Süt sığırcılığı işletmelerinde rastlanan IBR/IPV ve BVD virus enfeksiyonlarının infertilite olgularındaki rolü. AÜ Vet Fak Derg., 42(3): 381-387.

 

BURGU, İ., AKÇA, Y., ALKAN, F., ÖZKUL, A., ve KARAOĞLU, T. (1995) : Yenidoğan ishalli buzağılarda rotavirusların EM, PAGE ve ELISA ile çabuk teşhisi ve antijenik karakterizasyonu. A.Ü.Vet.Fak. Derg., 42(4): 491-498.

 

BURGU, İ.,.URMAN, H.K, AKÇA, Y., YONGUÇ, A.D., MELLOR, P.S., HAMBLIN, C., HAZIROĞLU, R., ALKAN, F., AKÇORA, A., ÖZKUL, A., EREN, H. and S.ALTINSAAT (1995) : Control of Akabane disease and surveillance of Bluetongue and Ephemeral Fever. United Nations Development Programme, AG:DP/TUR/86/017.FAO of the UN,Rome.

 

KORKUSUZ, F., KORKUSUZ, P., ÖZKUL, A., ERCAN, Z.S. and BURGU, İ. (1994) : Substanse P receptors on fibroblast like cells indicate neuroendocrin regulation of periosteal bone healing. J Bone and JointSurg, 18(2) :515-516.

 

BURGU, İ., AKÇA, Y., ALKAN, F., ÖZKUL, A., KARAOĞLU, T. and ÇABALAR, M. (1994) : Antibody prevalence of Caprine Arthritis Encephalitis Virus (CAEV) in goats in Turkey. Dtsch. tierärztl.Wschr. 101 :390-391.

 

ALAÇAM, T., ÖMÜRLÜ, H., ÖZKUL, A., GÖRGÜL, G. and MISIRLIGİL, A. (1993) : Cytotoxicity versus antibacterial activity of some antiseptics. J.Nihon Univ.Sch.Dent., 35(1): 22-27.

 

KORKUSUZ, F., ÖZKUL, A. and BURGU, İ. (1993) : Isolation and invitro reproduction of periosteal cells. Turkish J.Med Res., 11(3): 107-111.

 

BURGU, İ.and ÖZKUL, A. (1993) : Detection by cultural isolation of bovine virus diarrhea (BVD) virus following field infections in cattle and their fetuses. Dtsch.tierärztl.Wschr., 100 : 361-363.

 

BURGU, İ., ALKAN, F. ve ÖZKUL, A. (1992) : Hücre kültürleri ve sığır serumlarında Pestivirus kontaminasyonu. A.Ü.Vet.Fak.Derg., 39(3) :372-380.

 

SONAT, B.,.DALAT, D., BURGU, İ. ve ÖZKUL, A. (1992) : Kanal dolgu maddelerinin toksisite potansiyellerinin HeLa hücre kültürleri üzerindeki değerlendirilmeleri. A.Ü.Diş Hek.Fak.Derg., 19(1) :35-42

 

BURGU, İ., TOKER, A., AKÇA, Y., ALKAN, F., YAZICI, Z. ÖZKUL, A. (1992) : Türkiye’de Visna-Maedi enfeksiyonunun serolojik olarak araştırılması. A.Ü.Vet.Fak.Derg., 37(3) :538-553.

 

KOCABEYOĞLU, Ö., AKÇA, Y., TOKER, A., EMEKDAŞ, G., ÖZKUL, A.,  BURGU, İ. (1989) : 13 – 25 yaş grubundaki sağlıklı kişilerde Respiratory Syncytial Virus antikor düzeylerinin mikronötralizasyon testi ile araştırılması. Mikrobiyol Bült., 23 :116-120.